What does lactic dehydrogenase mean?

Lactical dehydrogenase (LDH) is an enzyme present in various cells of the human body, including muscle cells, heart cells, liver cells and blood cells. It plays an important role in the metabolism of lactic acid.

function of lactic dehydrogenase

LDH is responsible for catalyzing the conversion of pyruvic acid into lactic acid during anaerobic glycolysis. Glycolysis is a metabolic process that occurs in cell cytoplasm and is responsible for breaking glucose in smaller molecules to produce energy.

Under normal conditions, anaerobic glycolysis occurs when there is rapid energy demand and the amount of available oxygen is limited. During this process, pyruvic acid is converted to lactic acid by LDH.

Clinical Importance of Lactic Dehydrogenase

LDH dosage in the blood can be used as a cellular lesion marker. Increases in LDH levels may indicate damage to tissues, such as muscle injuries, liver disease, heart disease, hemolytic anemia, among other conditions.

In addition, LDH can also be used as a tumor activity marker. In some types of cancer, such as lymphoma and leukemia, LDH levels may be high due to rapid cell proliferation and tissue destruction.

How is the LDH exam?

LDH examination is performed through a blood sample. Blood is collected through a venous puncture sent for laboratory analysis. The results are expressed in units per liter (U/L) and may vary according to the age, gender and health conditions of the patient.

Conclusion

Lactical dehydrogenase is an important enzyme in lactic acid metabolism. It plays a fundamental role in energy production under low oxygen conditions. In addition, the ldh dosage in the blood can be used as a marker of cellular injury and tumor activity.

It is important to note that the interpretation of the results of the LDH examination should be done by a doctor, taking into account the patient’s clinical history and other complementary exams.